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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Iris Fixation via External Pentagram Suturing
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Buphthalmos development in adult: case report.

Mônica Alves1, Leonardo Tannus Malki, Eduardo Melani Rocha

  • 1Department of Ophthalmology, Otorrinolaringology and Head & Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - USP - Ribeirão Preto (SP), Brazil. monicalves@fmrp.usp.br

Arquivos Brasileiros De Oftalmologia
|March 9, 2013
PubMed
Summary

This case study details extensive globe enlargement (buphthalmos) in a young adult with hypohidrotic ectodermal dysplasia. It highlights a rare instance of secondary glaucoma in adulthood, linked to ocular surface disorders.

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Area of Science:

  • Ophthalmology
  • Genetics
  • Dermatology

Background:

  • Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disorder affecting ectodermal structures.
  • Ocular manifestations in HED can include dry eye and other ocular surface disorders.
  • Secondary glaucoma is a known complication in various ocular conditions.

Observation:

  • A young adult patient with HED presented with significant ocular surface issues.
  • The patient developed extensive globe enlargement, a condition known as buphthalmos.
  • This buphthalmos was attributed to secondary glaucoma.

Findings:

  • This case represents the first reported instance of buphthalmos in an adult patient with HED.
  • The secondary glaucoma developed in the context of pre-existing ocular surface disorders associated with HED.
  • The extensive globe enlargement underscores a severe, albeit rare, complication of HED.

Implications:

  • This report expands the understanding of potential ocular complications in HED into adulthood.
  • It emphasizes the importance of vigilant ophthalmological monitoring in patients with HED.
  • Further research may elucidate the specific mechanisms linking HED, ocular surface disease, and glaucoma development.