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MultIDIMensionality of IDIMs: intrinsic disorder in autoinhibition

Vladimir N Uversky1

  • 1Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA. vuversky@health.usf.edu

Structure (London, England : 1993)
|March 12, 2013
PubMed

Intrinsic disorder (ID) is crucial for the function of many proteins. The activity of some proteins is autoinhibited by their inhibitory modules (IMs). In this issue of Structure, Trudeau and colleagues showed multifarious roles of ID in controlling agility of IMs.

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