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Related Experiment Videos

The Dide-Botcazo syndrome: forgotten and misunderstood.

Lucio G Lazzarino De Lorenzo1, Dominic H Ffytche2, Eva Di Camillo1

  • 1SOC di Neurologia, Ospedale Civile, Gorizia, Italy.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|March 12, 2013
PubMed
Summary

Dide-Botcazo syndrome, characterized by visual deficits and memory impairment, results from bilateral posterior cerebral artery infarcts. This historical review revives the syndrome

Keywords:
AmnesiaAnton's syndromePosterior cerebral arteryVascular dementia

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Area of Science:

  • Neuroscience
  • Neurology
  • Vascular Neurology

Background:

  • The Dide-Botcazo syndrome, first described in 1902, links visual field defects, topographical disorientation, and amnesia to bilateral occipito-temporal lesions.
  • The syndrome was largely forgotten until its revival in the 1980s, with some later cases including visual anosognosia (Anton's syndrome).

Observation:

  • This review presents a historical analysis of the Dide-Botcazo syndrome.
  • A recent case with clinical features mirroring the original description is illustrated.

Findings:

  • Bilateral posterior cerebral artery infarcts are associated with visual and memory deficits.
  • The original Dide and Botcazo case study highlighted the role of the occipital lobe and inferior longitudinal fasciculus in memory.

Implications:

  • The Dide-Botcazo syndrome is proposed as a variant of vascular dementia.
  • It encompasses visual field deficits, memory impairment, and potentially visual perceptual, topographic, imagery, or dreaming deficits depending on lesion location.