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The cardiovascular manifestations of influenza: a systematic review

Zahra Raisi Estabragh1, Mamas A Mamas

  • 1Manchester Royal Infirmary, Central Manchester NHS Foundation Trust, Oxford Road, Manchester M13 9WL, UK.

International Journal of Cardiology
|March 12, 2013
PubMed

Insights

Influenza infection can cause serious cardiovascular complications, including myocarditis and increased heart attack risk. Vaccination may reduce cardiovascular mortality in high-risk individuals.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Influenza causes millions of severe illnesses and hundreds of thousands of deaths annually.
  • Cardiovascular complications are a significant concern associated with influenza infection.
  • These complications arise from direct viral effects on the heart or exacerbation of existing cardiovascular conditions.

Purpose of the Study:

  • To review the spectrum of cardiovascular complications linked to influenza.
  • To describe the presentation, clinical course, and management of these complications.
  • To highlight the impact of influenza on cardiovascular health and the role of vaccination.

Main Methods:

  • This is a review article.
  • Literature search on influenza and cardiovascular complications.
  • Synthesis of existing data on clinical presentation, outcomes, and management.

Main Results:

  • Influenza can lead to myocarditis, ranging from asymptomatic to fatal cases.
  • Pre-existing coronary artery disease patients face increased cardiovascular mortality during influenza epidemics.
  • Influenza outbreaks are associated with higher rates of myocardial infarction; vaccination shows protective effects.

Conclusions:

  • Influenza poses a significant risk for cardiovascular complications.
  • Early recognition and management are crucial for patients experiencing cardiac issues during influenza.
  • Influenza vaccination is a key strategy for reducing cardiovascular mortality in at-risk populations.

Keywords:
CardiacComplicationsInfluenza

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