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Sample Preparation of Mycobacterium tuberculosis Extracts for Nuclear Magnetic Resonance Metabolomic Studies
07:56

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Published on: September 3, 2012

Comparative analysis of genes encoding key steroid core oxidation enzymes in fast-growing Mycobacterium spp. strains

E Yu Bragin1, V Yu Shtratnikova, D V Dovbnya

  • 1Center of Innovations and Technologies "Biological Active Compounds and Their Applications", Russian Academy of Sciences, Moscow 119991, Russian Federation; G.K.Skryabin Institute of Biochemistry & Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation.

The Journal of Steroid Biochemistry and Molecular Biology
|March 12, 2013
PubMed

Keywords:
2,3-dehydroxyphenyl dioxygenase2-enoyl acyl-CoA hydratase2-hydroxypenta-2,4-dienoate hydratase3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase subunit3-ketosteroid-9α-hydroxylase3-ketosteroid-Δ(1)-dehydrogenase3β-hydroxysteroid-dehydrogenase4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase4-hydroxy-2-oxovalerate aldolase9-OH-AD9α-hydroxy androst-4-ene-3,17-dioneADADDAndrost-1,4-diene-3,17-dioneAndrost-4-ene-3,17-dioneBWABroadband-Wheeler AlignerCTABChoXChoX(D,E)EchA19FADFadA5FadD17FadD19FadE26FadE27FadE28Genome sequencingHSDHTH-type transcriptional repressorHsaAHsaABHsaBHsaCHsaDHsaEHsaFHsaGHsd4AHsd4BKSHKshAKshBKstRKstR2Ltp2Ltp3Ltp4MycobacteriumORFsPWMPhytosterolSNPSteroid bioconversionTesBYrbE4AYrbE4Bacetaldehyde dehydrogenaseacetyl-CoA acetyltransferaseacyl-CoA dehydrogenaseacyl-CoA synthetaseacyl-CoA thioesterase IIandrost-4-ene-3,17-dioneandrosta-1,4-diene-3,17-dionebase pairbpcetyl trimethyl ammonium bromidecholesterol oxidaseenoyl-CoA hydrataseflavin adenine dinucleotidehydroxysteroid dehydrogenaseintegral membrane proteinlipid transfer protein 4 (keto acyl-CoA thiolase)lipid-transfer protein 2lipid-transfer protein 3 (acetyl-CoA acetyltransferase)open reading framesposition weight matrixsingle nucleotide substitutionsubunit A of 3-ketosteroid-9α-hydroxylasesubunit B of 3-ketosteroid-9α-hydroxylasesΔ(1) KSTD

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