Related Experiment Video
Updated: May 13, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
A qualitative investigation of hypomania and depression in bipolar II disorder
Kathryn Fletcher1, Gordon Parker, Vijaya Manicavasagar
1School of Psychiatry, University of New South Wales, Kensington, NSW, Australia, k.fletcher@unsw.edu.au.
Abstract:
Psychological treatments may have differential impacts on bipolar (BP) sub-types, yet little is known about psychological processes in BP II disorder. We explored cognitive processes and behaviors mediating hypomania and depression in participants diagnosed with BP II disorder. Semi-structured interviews with 13 participants were analysed using interpretative phenomenological analysis. The majority were able to detect hypomanic and depressive prodromes, and describe behavioral responses to these mood states. Qualitative analyses revealed four theme clusters. Hypomania ascent beliefs described beliefs regarding identity, positioning hypomania as an enjoyable state preferable to depression. Hypomania descent beliefs referred to hypomania as a signal for depression, causing interpersonal difficulties. Beliefs about depression positioned depression as an abnormal, fearful state, impacting negatively interpersonally, occupationally and on self-perceptions. Finally, The impact of chronicity referred to shifts in coping strategies over time, moving from maladaptive to adaptive behavioral responses. Themes were interpreted within the framework of a cognitive model of BP disorder. Clinical implications for BP II disorder were discussed.
Related Concept Videos
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Depression: Overview
Depressive Disorders: MDD and Dysthymia
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...