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Heart rate variability analysis in patients with allergic rhinitis
Ming-Ying Lan1, Guo-She Lee, An-Suey Shiao
1Department of Otolaryngology, Taipei Veterans General Hospital, and Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Allergic rhinitis patients show altered autonomic nervous system function, specifically reduced sympathetic activity in the sitting position. This suggests autonomic dysfunction may contribute to allergic rhinitis.
Area of Science:
- Cardiology
- Immunology
- Autonomic Neuroscience
Background:
- Limited research explores the autonomic nervous system's role in allergic rhinitis.
- This study investigates autonomic function in allergic rhinitis using heart rate variability (HRV).
Purpose of the Study:
- To evaluate autonomic nervous system activity in patients with allergic rhinitis.
- To compare HRV parameters between allergic rhinitis patients and healthy controls.
Main Methods:
- Eleven allergic rhinitis patients and 13 healthy controls (aged 19-40) were enrolled.
- Diagnosis confirmed by clinical history, symptoms, and Phadiatop test.
- Electrocardiographic recordings were taken in sitting and supine positions for HRV analysis.
Main Results:
- No significant differences in HRV parameters were observed between groups in the supine position.
- In the sitting position, allergic rhinitis patients exhibited increased mean RR intervals and decreased LF% and LF/HF ratio.
- Unlike controls, allergic rhinitis patients showed no significant changes in HRV with posture changes.
Conclusions:
- Allergic rhinitis patients may experience impaired sympathetic modulation when sitting upright.
- Autonomic dysfunction is implicated in the underlying mechanisms of allergic rhinitis.
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