Related Experiment Video
Updated: May 13, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
Published on: January 26, 2016
1-(2-Amino-6-methyl-pyrimidin-4-yl)-N,N-dimethyl-piperidin-4-aminium chloride
S Sreenivasa1, K E Manojkumar, P A Suchetan
1Department of Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka 572 103, India.
Abstract:
In the title mol-ecular salt, C12H22N5(+)·Cl(-), the cation is protonated at the dimethyl-substituted tertiary N atom. The piperidine ring adopts a chair conformation with the exocyclic N-C bond in an equatorial orientation. The dihedral angle between the piperidine ring (all atoms) and the pyrimidine ring is 14.00 (1)°. In the crystal, the ions are connected by N-H⋯N hydrogen bonds, forming inversion dimers, which are further connected by N-H⋯Cl hydrogen bonds. Aromatic π-π stacking inter-actions [centroid-centroid separation = 3.4790 (9) Å] are also observed in the structure.
More Related Videos
12:02An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity
Published on: November 2, 2016
11:45Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Related Concept Videos
Acid Halides to Amides: Aminolysis
In the first step of the aminolysis mechanism, the amine attacks the carbonyl carbon of the acyl chloride to form a tetrahedral intermediate. In the second step, the carbonyl group is re-formed with the elimination of a chloride...
Structure of Amines
Nomenclature of Secondary and Tertiary Amines
Basicity of Heterocyclic Aromatic Amines
Nomenclature of Primary Amines
Nomenclature of Aryl and Heterocyclic Amines