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Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Ethyl 3-(2-eth-oxy-2-oxoeth-oxy)-6-(tri-fluoro-meth-yl)furo[3,2-c]quinoline-2-carboxyl-ate
B Garudachari1, Arun M Islor, A M Vijesh
1National Institute of Technology-Karnataka, Department of Chemistry, Medicinal Chemistry Laboratory, Surathkal, Mangalore 575 025, India.
Acta Crystallographica. Section E, Structure Reports Online
|March 12, 2013
Abstract:
In the title compound, C19H16F3NO6, a quinoline derivative featuring an annealated furan substituent, the mean planes of the carb-oxy substituents are at an angle of 74.3 (2)°. In the crystal, C-H⋯O contacts result in undulating chains along [110]. C-H⋯F contacts also occur. The shortest centroid-centroid distance between rings is 3.3376 (7) Å, involving two furan rings of neighbouring mol-ecules.
