2-(4-Chloro-phen-yl)-1,3-dioxane - localization of hydrogen atoms

Area of Science:

• Organic chemistry
• Crystallography

Background:

• 4-chloro-benzaldehyde derivatives are important in organic synthesis.
• Acetal protection is a common strategy in organic chemistry.

Purpose of the Study:

• To synthesize and characterize a novel acetal-protected derivative of 4-chloro-benzaldehyde.
• To investigate the solid-state structure and intermolecular interactions of the compound.

Main Methods:

• Chemical synthesis of the title compound.
• Single-crystal X-ray diffraction analysis to determine molecular and crystal structure.

Main Results:

• The compound C10H11ClO2 was successfully synthesized.
• The aliphatic ring adopts a chair conformation.
• Molecules form centrosymmetric dimers through weak C-H⋯O hydrogen bonds in the crystal.

Conclusions:

• The study provides a detailed structural characterization of a new 4-chloro-benzaldehyde derivative.
• The observed crystal packing highlights the role of weak interactions in supramolecular assembly.