Combination of solid phase extraction and surface-enhanced Raman spectroscopy for rapid analysis.

Area of Science:

• Analytical Chemistry
• Spectroscopy
• Materials Science

Background:

• Solid phase extraction (SPE) and surface-enhanced Raman spectroscopy (SERS) are powerful analytical techniques.
• Combining SPE and SERS can enhance analytical performance but requires integrated solutions.
• Developing stable and repeatable SERS-active materials for extraction is crucial for practical applications.

Purpose of the Study:

• To fabricate a novel SERS-active extraction column.
• To evaluate the performance of the column in terms of stability, repeatability, and analytical capabilities.
• To demonstrate the potential for rapid and simplified sample analysis.

Main Methods:

• Fabrication of a SERS-active extraction column using propanethiol modified silver dendrites.
• Integration of solid phase extraction and SERS principles within the column.
• Quantitative analysis of fluoranthene using the developed column.

Main Results:

• The fabricated column demonstrated high temporal stability under intensive laser radiation.
• Excellent repeatability was achieved for repeated extraction and elution cycles.
• Quantitative analysis of fluoranthene was successfully performed in the concentration range of 0.01-100 μg mL(-1).
• Extraction process completed in 10 s, with total analysis time under 30 s.

Conclusions:

• The developed SERS-active extraction column effectively combines SPE and SERS.
• The column facilitates rapid analysis with high reliability and accuracy.
• This approach significantly simplifies sample preparation and reduces overall analysis time.