Related Experiment Video

Updated: May 13, 2026

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
08:53

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Published on: April 16, 2019

500-fold efficacy increase in siRNA delivery

Lisa Parks

    Future Medicinal Chemistry
    |March 13, 2013
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    MISSION esiRNA for RNAi Screening in Mammalian Cells
    15:31

    MISSION esiRNA for RNAi Screening in Mammalian Cells

    Published on: May 12, 2010

    Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy
    15:55

    Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy

    Published on: June 21, 2013

    Related Experiment Videos

    Last Updated: May 13, 2026

    Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
    08:53

    Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

    Published on: April 16, 2019

    MISSION esiRNA for RNAi Screening in Mammalian Cells
    15:31

    MISSION esiRNA for RNAi Screening in Mammalian Cells

    Published on: May 12, 2010

    Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy
    15:55

    Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy

    Published on: June 21, 2013

    Related Concept Videos

    Experimental RNAi02:15

    Experimental RNAi

    RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
    siRNA - Small Interfering RNAs02:30

    siRNA - Small Interfering RNAs

    Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
    In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the ATP-dependent...

    Articles linked to this work by shared authors, journal, and citation graph.

    Developing Provider-Co-Created Prototypes Addressing Equity-Related Barriers in Liver Transplantation for Hepatocellular Carcinoma.

    medRxiv : the preprint server for health sciences·2026

    Developing a Tool to Assess Needs of AYA Cancer Survivors in Rural, Medically Underserved Regions of Southwestern Indiana.

    Journal of adolescent and young adult oncology·2025

    Information overload, financial constraints, and psychological burdens are among the barriers faced by marginalized groups seeking curative treatments for HCC.

    Hepatology communications·2025

    Unlocking success: community engagement for enhanced HIV care outcomes.

    Research involvement and engagement·2024

    Unlocking Success: Community Engagement for Enhanced HIV Care Outcomes.

    Research square·2024

    Human-centered designed communication tools for obesity prevention in early life.

    Preventive medicine reports·2023

    Integrated <i>in vitro</i> and <i>in silico</i> evaluation of adamantane-1,2,3-triazole hybrids as potential <i>α</i>-glucosidase inhibitors.

    Future medicinal chemistry·2026

    Synthesis of thiosemicarbazone derivatives of thiophene-2-carboxylic acid as potent urease inhibitors: <i>in vitro</i> evaluation, molecular docking, and density functional theory analysis.

    Future medicinal chemistry·2026

    Unlocking new antimicrobial leads in the last decade: exploring quinolin-2-one based hybrids' synthesis, action, SAR, and challenges in tackling antimicrobial resistance.

    Future medicinal chemistry·2026

    Oxazole-4,5-dicarboxylate derivatives as multifunctional targets against oral cancer and <i>Streptococcus mutans</i> oral pathogens.

    Future medicinal chemistry·2026

    Exploring thiazole conjugates as cholinesterase inhibitors for Alzheimer's disease treatment.

    Future medicinal chemistry·2026

    Bridging the green skills gap: a framework to align the pharmaceutical workforce with sustainable drug discovery.

    Future medicinal chemistry·2026

    Retracted Publications Related to Statistics: A Scopus-Based Bibliometric Analysis.

    Journal of Korean medical science·2026

    Inference about the ratio of age-standardized rates between two overlapping populations.

    Statistical methods in medical research·2026

    Five-year survival outcomes from TRANSCEND NHL 001 of lisocabtagene maraleucel in R/R LBCL.

    Blood·2026

    When can whole-genome SNP heritability be reliably estimated from summary statistics?

    bioRxiv : the preprint server for biology·2026

    A Simple Analytic Approach to Regression with or without Interaction Terms: Integrating the Covariance Structure Model and the Delta Method.

    Psychometrika·2026

    Computing large deviations of first-passage-time statistics in open quantum systems: Two methods.

    Physical review. E·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us