TEM-187, a new extended-spectrum β-lactamase with weak activity in a Proteus mirabilis clinical strain

Stéphane Corvec1, Racha Beyrouthy, Lise Crémet

  • 1Service de Bactériologie-Hygiène, CHU de Nantes, Institut de Biologie, Nantes, France. stephane.corvec@chu-nantes.fr

Insights

A novel TEM-type beta-lactamase, TEM-187, was discovered in a Proteus mirabilis strain from a long-term-care facility. This finding highlights the growing diversity of beta-lactamases and their potential spread.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Antimicrobial Resistance

Background:

  • Proteus mirabilis is a common cause of urinary tract infections, particularly in healthcare settings.
  • The emergence of antibiotic resistance, especially beta-lactamases, poses a significant threat to public health.
  • Extended-spectrum beta-lactamases (ESBLs) confer resistance to a wide range of antibiotics.

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