Related Experiment Video

Updated: May 13, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

[Perioperative management in children with sleep apnea syndrome (SAS) undergoing adenoidotonsillectomy]

Ju Mizuno1, Mikiko Nemoto, Tomoko Sato

  • 1Department of Anesthesiology and Intensive Care Unit, Teikyo University School of Medicine, Tokyo 173-8605.

Masui. the Japanese Journal of Anesthesiology
|March 14, 2013
PubMed

Insights

Children with sleep apnea syndrome (SAS) need careful monitoring after anesthesia due to increased opioid sensitivity. Preoperative sleep studies can predict and guide management of postoperative respiratory depression.

Area of Science:

  • Anesthesiology and Sleep Medicine

Context:

  • Children with sleep apnea syndrome (SAS) exhibit heightened sensitivity to opioid agonists, particularly after recurrent hypoxia.
  • Postoperative respiratory complications, including apnea and hypopnea, are significant concerns during emergence from general anesthesia in these patients.

Purpose:

  • To highlight the importance of preoperative assessment for SAS using polysomnography (PSG) parameters like apnea-hypopnea index (AHI), oxygen desaturation index (ODI), and minimum SpO2.
  • To provide recommendations for perioperative management in pediatric SAS patients undergoing procedures such as adenotonsillectomy.

Summary:

  • Preoperative PSG assessment aids in predicting postoperative respiratory depression.
  • Reducing opioid agonist dosage during anesthesia maintenance is crucial.
  • Intensive postoperative monitoring, including respiratory and SpO2 tracking, along with oxygen administration, is essential.
  • Preparedness for airway management, nCPAP, and artificial ventilation is necessary for managing potential respiratory depression.

Impact:

  • Informed perioperative strategies can mitigate risks associated with general anesthesia in children with SAS.
  • Optimized anesthetic and postoperative care can improve patient outcomes and reduce morbidity.
  • Early identification and management of respiratory events enhance patient safety.

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