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05:10
Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Key issues in the pharmaceutical industry: consequences on R&D.
1University of Cambridge, Institute of Biotechnology, Tennis Court Road, Cambridge, CB2 1QT, UK nafees_malik@hotmail.com.
Expert Opinion on Drug Discovery
|March 14, 2013
Summary
Drug discovery faces increasing challenges, impacting pharmaceutical companies. This article explores R&D issues and suggests strategies for success in pharmaceutical innovation.
Area of Science:
- Pharmaceutical Science
- Drug Development
- Healthcare Economics
Background:
- Drug discovery is increasingly complex due to scientific, financial, and political factors.
- Rising research and development (R&D) costs and declining new drug approvals challenge the pharmaceutical industry.
- Patent expirations, generic competition, and decreased public/investor confidence further complicate the landscape.
Purpose of the Study:
- To discuss the critical issues confronting pharmaceutical companies.
- To analyze the implications of these challenges on the drug research and development (R&D) process.
- To propose strategic changes for pharmaceutical R&D to ensure future success.
Main Methods:
- Qualitative analysis of industry trends.
- Review of economic and regulatory factors impacting drug development.
- Synthesis of challenges and strategic recommendations for R&D.
Main Results:
- Pharmaceutical R&D is hampered by escalating costs, stringent regulatory standards (e.g., FDA), and patent cliffs.
- Industry faced declining public and investor confidence due to pricing, safety, and trial failures.
- Significant shifts in R&D strategy are necessary for pharmaceutical companies to navigate these hurdles.
Conclusions:
- Pharmaceutical companies must adapt R&D strategies to overcome escalating costs and regulatory hurdles.
- Innovation in drug discovery requires addressing economic, political, and scientific complexities.
- Strategic adjustments are crucial for maintaining industry viability and public trust.
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