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Retinal and choroidal thickness in myopic anisometropia
Stephen J Vincent1, Michael J Collins, Scott A Read
1Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia. sj.vincent@qut.edu.au.
Investigative Ophthalmology & Visual Science
|March 14, 2013
Summary
In nonamblyopic myopic anisometropes, retinal thickness was similar between eyes. However, the more myopic eye had significantly thinner choroidal thickness, correlating with axial length differences.
Area of Science:
- Ophthalmology
- Retinal imaging
- Optical coherence tomography
Background:
- Myopic anisometropia, a condition with unequal refractive error between eyes, can impact ocular development.
- Understanding interocular differences in retinal and choroidal structures is crucial for myopia research.
Purpose of the Study:
- To compare retinal thickness (RT) and choroidal thickness (ChT) between fellow eyes in nonamblyopic myopic anisometropes.
- To investigate the relationship between these thicknesses and axial length (AXL) differences.
Main Methods:
- Spectral domain optical coherence tomography (SD-OCT) was used to examine 22 nonamblyopic myopic anisometropes.
- Customized software facilitated image registration and averaging for enhanced quality.
- Retinal and choroidal thicknesses were manually measured up to 2.5 mm from the fovea; axial length was measured using optical low coherence biometry.
Main Results:
- No significant difference in foveal retinal thickness was observed between fellow eyes.
- Subfoveal choroidal thickness was significantly thinner in the more myopic eye (252 ± 46 μm) compared to the less myopic eye (286 ± 58 μm).
- A moderate negative correlation existed between interocular subfoveal ChT difference and interocular AXL difference (r = -0.50). Asian participants showed more symmetrical nasal-temporal ChT profiles.
Conclusions:
- Retinal thickness is comparable between fellow eyes in myopic anisometropes.
- The subfoveal choroid is thinner in the more myopic (longer) eye.
- Interocular asymmetry in choroidal thickness is associated with interocular differences in axial length.