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Updated: May 13, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Patterns of short saphenous vein incompetence
M I Qureshi1, T R A Lane, H M Moore
1Academic Section of Vascular Surgery, Imperial College London, 4 North, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK.
Short saphenous vein (SSV) reflux is significant in chronic venous disease (CVD), affecting 3.5% of patients and potentially causing venous ulcers. Its role in recurrent disease and secondary CVD requires further investigation.
Area of Science:
- Vascular Surgery
- Phlebology
- Venous Disease Research
Background:
- The clinical significance of short saphenous vein (SSV) reflux in chronic venous disease (CVD) is not well understood.
- SSV incompetence prevalence is approximately 3.5%, increasing with venous insufficiency severity.
- SSV reflux is associated with lateral malleolar venous ulceration.
Purpose of the Study:
- To investigate the origin and significance of SSV reflux in both primary and secondary CVD.
- To explore the patterns of SSV reflux and its implications in recurrent venous disease.
Main Methods:
- Review of existing literature and clinical data on SSV reflux.
- Analysis of SSV reflux patterns in primary and secondary CVD.
- Assessment of the association between SSV reflux and venous ulceration.
Main Results:
- The most frequent pattern of reflux involves the entire length of the SSV.
- SSV reflux may contribute to disease recurrence due to complex saphenopopliteal anatomy.
- Prevalence of SSV incompetence increases with the progression of clinical venous insufficiency.
Conclusions:
- SSV reflux is an important factor in chronic venous disease, particularly associated with ulceration.
- Further research is needed to clarify the impact of SSV reflux in secondary venous disease and deep venous incompetence.
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