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Serum uric acid level in acute stroke patients
Masoud Mehrpour1, Mahbubeh Khuzan, Neda Najimi
1MD., MPH Assistant professor, Stroke center, Firoozgar General Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Medical Journal of the Islamic Republic of Iran
|March 14, 2013
Summary
High uric acid levels are common in acute stroke patients and linked to higher triglycerides and LDL cholesterol. This suggests hyperuricemia may be a risk factor for stroke.
Area of Science:
- Neurology
- Cardiology
- Metabolic Disorders
Background:
- The association between uric acid and vascular disease, including acute stroke, remains debated.
- Limited data exists on uric acid levels in acute stroke patients and their relation to risk factors.
Purpose of the Study:
- To determine serum uric acid levels in patients experiencing acute stroke.
- To investigate the relationship between serum uric acid and established cerebrovascular risk factors.
Main Methods:
- A cross-sectional study involving 55 acute stroke patients admitted between September 2010 and March 2011.
- Analysis of clinical records and serum uric acid levels using SPSS software.
- Evaluation of correlations between uric acid levels and various clinical parameters.
Main Results:
- Mean serum uric acid was 5.94±1.70 mg/dl, with 47.3% of patients exhibiting hyperuricemia.
- Hyperuricemia correlated positively with triglyceride and LDL cholesterol levels.
- Uric acid levels were higher in men than women and showed a negative correlation with age.
Conclusions:
- The high prevalence of hyperuricemia in acute stroke patients warrants consideration.
- Elevated uric acid, alongside increased triglycerides and LDL cholesterol, suggests it may be a risk factor for acute stroke.
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