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Racial differences in HbA1c: a cross-sectional analysis of a Brazilian public primary care population

Veronica A de Miranda1, Rubens A Cruz Filho, Talita Sposito de Oliveira

  • 1Universidade Federal do Rio de Janeiro, Rua Aloísio da Silva Gomes, 50, Granja dos Cavaleiros, Macaé, RJ, CEP 27930-560, Brazil. veronicaalcoforado@hotmail.com

Primary Care Diabetes
|March 15, 2013
PubMed

Insights

Black individuals exhibit higher glycated hemoglobin (HbA1c) levels and diabetes risk. Familial aggregation of HbA1c is stronger in Black Brazilians, suggesting genetic influences on diabetes complications.

Area of Science:

  • Cardiology
  • Endocrinology
  • Genetics

Background:

  • Black populations exhibit higher glycated hemoglobin (HbA1c) levels.
  • Diabetes-related complications disproportionately affect Black individuals.

Purpose of the Study:

  • Investigate if HbA1c prevalence varies by skin color.
  • Examine familial aggregation of skin color and HbA1c.

Main Methods:

  • Utilized the CAMELIA study population in Brazil (2006-2007).
  • Collected data via questionnaires, medical consultations, and anthropometric assessments.
  • Measured HbA1c using immunoturbidimetry.

Main Results:

  • Compared data for Black (25.5%), Mulatto (44.7%), and White (28.8%) participants.
  • Black individuals had lower income/education, higher diabetes/hypertension rates, and elevated HbA1c.
  • Sibling HbA1c correlations were significantly higher in Blacks (86%) versus Whites/Mulattos (50%).

Conclusions:

  • Brazilian Black patients require increased attention for diabetes prevention.
  • Further longitudinal studies are necessary to determine the clinical impact of altered HbA1c levels.
Abstract

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