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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Related Experiment Video

Updated: Feb 24, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Management rules to detect melanoma.

Aimilios Lallas¹, Iris Zalaudek, Zoe Apalla

¹Dermatology and Skin Cancer Unit, Arcispedale Santa Maria Nuova IRCCS, IT- 42100 Reggio Emilia, Italy.

Dermatology (Basel, Switzerland)

|March 15, 2013

Summary

This summary is machine-generated.

Detecting inconspicuous melanomas requires specific strategies beyond visual inspection. Integrating clinical and dermoscopic criteria is crucial for accurate melanoma diagnosis.

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Last Updated: Feb 24, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

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Published on: June 7, 2019

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Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Published on: November 25, 2011

Area of Science:

Dermatology
Oncology

Background:

Melanoma diagnosis is typically straightforward clinically and dermoscopically.
Challenges arise with melanomas exhibiting inconspicuous morphology.

Observation:

Morphological assessment alone is insufficient for diagnosing subtle melanomas.
A comprehensive approach integrating multiple diagnostic modalities is necessary.

Findings:

Seven practical rules are proposed for managing difficult melanoma cases.
These rules emphasize a holistic strategy combining clinical, dermoscopic, and histopathologic criteria.

Implications:

Adopting these rules can improve early melanoma detection rates.
Enhanced diagnostic strategies are vital for improving patient outcomes in melanoma management.