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Does tardive dysmentia really exist?

Sagar Lavania1, Samir Kumar Praharaj, Hariender Singh Bains

  • 1Dept. of Psychiatry, Sarojini Naidu Medical College, Agra, India.

The Journal of Neuropsychiatry and Clinical Neurosciences
|March 15, 2013
PubMed
Summary
This summary is machine-generated.

Tardive dysmentia symptoms are common in schizophrenia patients, but the full syndrome is rare. These symptoms correlate with increased psychopathology and tardive dyskinesia, suggesting a link in chronic schizophrenia.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Tardive dysmentia is theorized as the behavioral correlate of tardive dyskinesia in schizophrenia.
  • The relationship between tardive dysmentia, tardive dyskinesia, and general psychopathology remains debated.

Purpose of the Study:

  • To investigate the prevalence of tardive dysmentia symptoms and the full syndrome in chronic schizophrenia patients.
  • To examine the association between tardive dysmentia, psychopathology, and tardive dyskinesia.

Main Methods:

  • 123 inpatients with chronic schizophrenia were assessed for tardive dysmentia symptoms/signs.
  • Psychopathology and tardive dyskinesia were evaluated using standardized scales.

Main Results:

  • 19.5% of patients exhibited at least one tardive dysmentia symptom/sign; only 0.8% met full syndromal criteria.
  • Patients with tardive dysmentia showed higher psychopathology scores and Abnormal Involuntary Movement Scale (AIMS) scores.
  • Tardive dysmentia was associated with a higher proportion of women, family psychiatric history, and persistent tardive dyskinesia.

Conclusions:

  • Tardive dysmentia symptoms are frequently observed in chronic schizophrenia.
  • The complete tardive dysmentia syndrome appears to be rare in this population.
  • Findings suggest a potential link between tardive dysmentia, psychopathology, and tardive dyskinesia.