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Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
[Central nervous system embolism in the course of infective endocarditis]
Maciej Grabowski1, Maria Jaworska-Wilczyńska, Urszula Ablewska
1Instytut Kardiologii, ul. Alpejska 42, 04-628 Warszawa, Poland. grabi71@yahoo.com
Insights
Infective endocarditis (IE) causes constant stroke risk and mortality despite treatment advances. Early detection of silent brain embolism via neuroimaging is crucial for managing cardiac surgery decisions.
Area of Science:
- Cardiology
- Neurology
- Infectious Diseases
Abstract:
Despite the progress made in diagnosis and treatment of heart valve diseases, the incidence of infective endocarditis (IE) remains constant. It is still associated with high mortality and high rate of embolic complications, including most dangerous one, i.e. stroke. It has a significant impact on further treatment and qualifications for cardiac surgery. In this paper, the authors discuss the epidemiology, mechanisms of stroke and its impact on the qualifications for cardiac surgery. The authors discuss the problem of clinically silent central nervous system embolism in the course of IE and the usefulness of neuroimaging and markers of central nervous system damage in diagnosis of cerebral embolism.
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