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Low-contrast dose protection protocol for diagnostic computed tomography in patients at high-risk for
Masafumi Kidoh1, Takeshi Nakaura, Kazuo Awai
1Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan. masafkidoh@yahoo.co.jp
Objective:
To evaluate the safety of a low-contrast dose computed tomography (CT) protocol for patients with renal insufficiency for contrast-induced nephropathy.
Methods:
One hundred forty-three patients with renal insufficiency who underwent low-contrast dose-enhanced abdominal CT were reviewed. Another group of 327 patients who received unenhanced CT was reviewed as a control group. Baseline serum creatinine and estimated glomerular filtration rate (eGFR) levels were obtained for all patients to determine the contrast dosing (1.6 and 1.0 mL/kg for patients with eGFR levels 30-59 and 15-29). We compared the incidence of acute kidney injury between the groups.
Results:
There were no significant differences in the incidence of acute kidney injury between the low-contrast dose and unenhanced CT protocols (9.1% vs 8.3%, P = 0.77). None of the patients with renal dysfunction required postprocedure dialysis.
Conclusion:
The low-contrast dose CT protocol might enable us to perform a contrast-enhanced study without any major safety concerns.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...