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Related Experiment Video

Updated: May 13, 2026

Measurement of Protein Turnover Rates in Senescent and Non-Dividing Cultured Cells with Metabolic Labeling and Mass Spectrometry

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Published on: April 6, 2022

Lipid turnover during senescence.

Manuel A Troncoso-Ponce¹, Xia Cao, Zhenle Yang

¹Instituto de la Grasa, CSIC, Avda. Padre Garcia Tejero 4, 41012 Seville, Spain.

Plant Science : an International Journal of Experimental Plant Biology

|March 19, 2013

Summary

This summary is machine-generated.

Plant leaf senescence involves lipid turnover, but key lipases and metabolic pathways remain unclear. This study identifies coordinated gene expression patterns, including 68 lipases, during Arabidopsis leaf senescence.

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Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published on: March 8, 2020

Area of Science:

Plant Molecular Biology
Biochemistry
Plant Physiology

Background:

Triacylglycerol turnover provides energy for seedlings, but lipid turnover during plant senescence is less understood.
While β-oxidation is induced during senescence, Arabidopsis leaf fatty acid turnover is significantly slower than in seedlings.
The specific lipases and metabolic fates of fatty acids during senescence are largely unknown.

Purpose of the Study:

To provide an overview of senescence-related glycerolipid turnover and its potential functions.
To explore how lipid turnover during senescence could be manipulated to enhance crop nutritional value.
To investigate the regulation of lipid turnover by analyzing gene expression during Arabidopsis leaf senescence.

Main Methods:

Development of a database compiling and plotting transcript expression of lipid-related genes during natural Arabidopsis leaf senescence.
Analysis of coordinated gene expression patterns, including down-regulation of biosynthesis genes and up-regulation of catabolic genes.
Identification of putative lipase genes involved in lipid degradation.

Main Results:

Identified coordinated down-regulation of lipid biosynthesis genes during senescence.
Observed contrasting up-regulation of gene groups involved in lipid catabolism, including 68 putative lipases.
Established a valuable resource for studying gene regulation in plant senescence.

Conclusions:

Senescence involves complex regulation of lipid turnover, with distinct sets of genes being activated and repressed.
The identification of numerous putative lipases suggests their critical role in degrading diverse lipid structures during senescence.
Understanding these regulatory mechanisms offers potential for improving crop energy density and nutritional content.