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Updated: May 13, 2026
12:08
Generating Transgenic Plants with Single-copy Insertions Using BIBAC-GW Binary Vector
Published on: March 28, 2018
Generating high temperature tolerant transgenic plants: Achievements and challenges
Anil Grover1, Dheeraj Mittal, Manisha Negi
1Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi 110021, India. agrover@south.du.ac.in
Summary
Developing high-temperature tolerant plants is crucial for global warming. Researchers explore genetic strategies, including heat shock proteins and other factors, to enhance plant survival under heat stress.
Area of Science:
- Plant Science
- Genetics
- Biotechnology
Background:
- Global warming and climate change necessitate plants with high temperature tolerance.
- Plant cells adapt to heat stress by genetic reprogramming for survival.
- Current strategies focus on genetic modifications for heat tolerance.
Purpose of the Study:
- To review and discuss methods for producing high-temperature tolerant transgenic plants.
- To highlight key genetic factors and proteins involved in heat stress response.
- To identify limitations in field cultivation of these plants.
Main Methods:
- Over-expression of heat shock protein genes.
- Altering levels of heat shock factors (HSFs).
- Modulating expression of trans-acting factors like DREB2A, bZIP28, and WRKY proteins.
Main Results:
- Transgenic plants show enhanced tolerance through various genetic modifications.
- Proteins involved in osmotic adjustment, ROS scavenging, and membrane lipid saturation contribute to tolerance.
- Cyclic nucleotide gated calcium channels and calmodulin/kinase pathways are key regulators.
Conclusions:
- Multiple genetic and molecular pathways can be targeted to achieve high temperature tolerance in plants.
- Further research is needed to overcome limitations for field cultivation of tolerant transgenic plants.
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