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Published on: March 28, 2025
Interdisciplinary expert consensus document on management of type B aortic dissection
Rossella Fattori1, Piergiorgio Cao, Paola De Rango
1Department of Interventional Cardiology, San Salvatore Hospital, Pesaro, Italy. rossella.fattori@unibo.it
Insights
Treatment algorithms for type B aortic dissection suggest medical management for uncomplicated cases. Complicated dissections may require urgent or delayed aortic repair, with varying mortality rates for medical, open surgery, and thoracic endovascular repair (TEVAR).
Area of Science:
- Cardiovascular Surgery
- Vascular Medicine
- Medical Algorithms
Background:
- Type B aortic dissection management requires evidence-based treatment strategies.
- A multidisciplinary panel reviewed 63 studies (2006-2012) involving over 6,000 patients.
- Data analyzed medical, open surgery, and thoracic endovascular repair (TEVAR) outcomes.
Framework:
- Developed consensus-based treatment algorithms for acute, subacute, and chronic type B aortic dissection.
- Utilized a consensus method based on a comprehensive literature review.
- Algorithms differentiate management for uncomplicated versus complicated dissections.
Implementation:
- Acute uncomplicated type B aortic dissection: Managed with medical therapy and close image monitoring.
- Complicated acute type B aortic dissection: Requires urgent aortic repair (TEVAR or open surgery).
- Subacute and chronic type B aortic dissection: Medical management for uncomplicated cases; delayed repair indicated for specific adverse outcome predictors.
Implications:
- Medical treatment shows lower early mortality for uncomplicated acute type B aortic dissection.
- TEVAR and open surgery have higher early mortality, particularly for complicated cases.
- Algorithms provide a proposed strategy for type B aortic dissection management, acknowledging evidence limitations.
Abstract:
An expert multidisciplinary panel in the treatment of type B aortic dissection reviewed available literature to develop treatment algorithms using a consensus method. Data from 63 studies published from 2006 to 2012 were retrieved for a total of 1,548 patients treated medically, 1,706 patients who underwent open surgery, and 3,457 patients who underwent thoracic endovascular repair (TEVAR). For acute (first 2 weeks) type B aortic dissection, the pooled early mortality rate was 6.4% with medical treatment and increased to 10.2% with TEVAR and 17.5% with open surgery, mostly for complicated cases. Limited data for treatment of subacute (2 to 6 weeks after onset) type B aortic dissection showed an early mortality rate of 2.8% with TEVAR. In chronic (after 6 weeks) type B aortic dissection, 5-year survival of 60% to 80% was expected with medical therapy because complications were likely. If interventional treatment was applied, the pooled early mortality rate was 6.6% with TEVAR and 8.0% with open surgery. Medical treatment of uncomplicated acute, subacute, and chronic type B aortic dissection is managed with close image monitoring. Hemodynamic instability, organ malperfusion, increasing periaortic hematoma, and hemorrhagic pleural effusion on imaging identify patients with complicated acute type B aortic dissection requiring urgent aortic repair. Recurrence of symptoms, aortic aneurysmal dilation (>55 mm), or a yearly increase of >4 mm after the acute phase are predictors of adverse outcome and need for delayed aortic repair ("complicated chronic aortic dissections"). The expert panel is aware that this consensus document provides proposal for strategies based on nonrobust evidence for management of type B aortic dissection, and that literature results were largely heterogeneous and should be interpreted cautiously.
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