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Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
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Methods of Nuclear Reprogramming01:24

Methods of Nuclear Reprogramming

Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for injury repair.
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Updated: May 13, 2026

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
10:28

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

Synthetic biology: programming cells for biomedical applications.

Maximilian Hörner1, Nadine Reischmann, Wilfried Weber

  • 1Faculty of Biology, University of Freiburg, Germany.

Perspectives in Biology and Medicine
|March 19, 2013
PubMed
Summary

Synthetic biology rationally designs biological systems using modular parts. This review highlights its biomedical applications, including drug delivery, drug discovery, and understanding host-parasite dynamics for biopharmaceutical innovation.

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Area of Science:

  • Synthetic biology
  • Bioengineering
  • Biomedical engineering

Background:

  • Synthetic biology integrates biology, chemistry, and engineering for rational design.
  • Early work focused on proof-of-principle modular systems.
  • Current research targets health, environmental, and energy applications.

Purpose of the Study:

  • To review recent synthetic biology approaches for biomedical applications.
  • To illustrate applications across the synthetic biology design hierarchy: parts, devices, and systems.
  • To demonstrate the potential of synthetic biology in the biopharmaceutical industry.

Main Methods:

  • Review of recent literature on synthetic biology in biomedicine.
  • Categorization of applications based on the synthetic biology design hierarchy.
  • Examples of synthetic biological parts, devices, and multicellular systems.

Main Results:

  • Synthetic biological parts enable the creation of novel drug-delivery tools.
  • Synthetic biological devices accelerate the discovery of new drugs.
  • Multicellular synthetic ecosystems offer insights into host-parasite population dynamics.

Conclusions:

  • Synthetic biology offers innovative solutions for the biopharmaceutical sector.
  • The modular engineering approach facilitates the development of complex biological systems.
  • This discipline holds significant promise for advancing healthcare and biotechnology.