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Variable-column bubble oxygenator. A new system for bubble oxygenation
The Journal of Thoracic and Cardiovascular Surgery
|April 1, 1975
Summary
A novel bubble oxygenator with adjustable dimensions was developed for open-heart surgery. This adaptable device ensured satisfactory oxygenation across 2,700 procedures with minimal adverse effects on patient blood parameters.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Medical Device Development
Background:
- Traditional bubble oxygenators have limitations in adapting oxygenation capacity to diverse patient needs.
- The development of advanced cardiopulmonary bypass equipment is crucial for improving surgical outcomes.
Purpose of the Study:
- To introduce and evaluate a newly developed bubble oxygenator with adjustable dimensions.
- To assess the efficacy and safety of this oxygenator in a large cohort of open-heart surgeries.
Main Methods:
- The novel bubble oxygenator was utilized in 2,700 open-heart operations.
- Detailed physiological and hematological studies were conducted on a subset of 50 patients.
- Key parameters including hemolysis, fibrinogen, platelet counts, and blood gas levels were monitored.
Main Results:
- Satisfactory oxygenation (PO2) was consistently achieved.
- Average hemolysis was 38.67 mg/dL over a mean perfusion time of 69 minutes.
- Fibrinogen and platelet levels decreased by 14% and 25%, respectively, with other blood parameters remaining within normal ranges.
Conclusions:
- The adjustable bubble oxygenator is effective and safe for cardiopulmonary bypass.
- Its adaptable design allows for tailored oxygenation capacity, meeting varied patient requirements.
- The device demonstrates good performance with acceptable levels of hemolysis and minimal impact on coagulation factors.