Normobaric oxygen therapy for scleral ischemia or melt
Farideh Sharifipour1, Mahmoodreza Panahi-Bazaz, Esmaeil Idani
1Department of Ophthalmology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Journal of Ophthalmic & Vision Research
|March 19, 2013
Summary
Normobaric oxygen (NBO) therapy effectively treats scleral ischemia or melt, promoting healing and vascularization. This non-invasive approach offers a promising alternative to surgery for these ocular conditions.
Area of Science:
- Ophthalmology
- Medical Therapy
Background:
- Scleral ischemia and melt are serious conditions requiring effective treatment.
- Conventional therapies may fail or be insufficient for scleral melt or ischemia.
Purpose of the Study:
- To evaluate the efficacy of normobaric oxygen (NBO) therapy in treating scleral ischemia or melt.
- To assess NBO as a potential non-invasive treatment for ocular surface disorders.
Main Methods:
- A prospective interventional case series involving 9 eyes of 8 patients with scleral ischemia/melt.
- Normobaric oxygen (NBO) therapy administered at 100% concentration, 10 L/min via face mask for 1 hour twice daily.
- Treatment continued until complete vascularization of ischemic areas was observed.
Main Results:
- All patients demonstrated epithelialization and vascularization of the ischemic sclera following NBO therapy.
- The healing process initiated within 3-4 days and completed in an average of 18.1 days.
- Patients remained clinically stable during a 9-month follow-up period.
Conclusions:
- Normobaric oxygen (NBO) therapy is an effective treatment for scleral ischemia or melt.
- NBO therapy facilitates scleral repair and conjunctival defect healing.
- NBO presents a viable non-invasive alternative to surgical interventions for these conditions.
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