Related Experiment Video
Updated: Aug 5, 2026

05:14
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Comparative Vector Analysis of Astigmatic Changes After Small-incision Lenticule Extraction versus Femtosecond Laser
Mai Hong Phan1, Luong Minh Huynh1,2, Say Kiang Foo2
1Ho Chi Minh City Eye Hospital, Ho Chi Minh, Vietnam.
Journal of Ophthalmic & Vision Research
|August 4, 2026
Summary
Small-incision lenticule extraction (SMILE) and femtosecond laser in-situ keratomileusis (FS-LASIK) offer similar visual outcomes for myopia with high astigmatism. Both procedures demonstrate comparable efficacy, predictability, and safety in correcting these refractive errors.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- High astigmatism presents unique challenges in refractive surgery.
- Small-incision lenticule extraction (SMILE) and femtosecond laser in-situ keratomileusis (FS-LASIK) are advanced laser vision correction techniques.
- Comparing visual outcomes is crucial for patient selection and surgical planning.
Purpose of the Study:
- To compare the visual outcomes of SMILE versus FS-LASIK.
- To evaluate efficacy, predictability, and safety in eyes with myopia and high astigmatism.
- To analyze refractive and astigmatic correction between the two surgical methods.
Main Methods:
- Retrospective study at a tertiary eye hospital (January 2021 - December 2022).
- Inclusion criteria: myopia up to -10.00 D and cylinder ≥ 2.50 D.
- Comparison of 170 eyes (83 SMILE, 87 FS-LASIK) with 3-month follow-up.
Main Results:
- No significant difference in uncorrected visual acuity (UCVA) or spherical equivalent (SEQ) between SMILE and FS-LASIK (P > 0.05).
- High percentages of eyes achieved 20/20 UDVA: 90.4% (SMILE) vs. 80.46% (FS-LASIK).
- Comparable outcomes in target-induced astigmatism, difference vector, and angle of error (P > 0.05).
Conclusions:
- SMILE and FS-LASIK show comparable efficacy, predictability, and safety for correcting myopia with high astigmatism (≥ 2.50 D).
- Both procedures are effective options for patients with complex refractive errors.
- Further research may explore long-term outcomes and patient satisfaction.
