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Updated: May 13, 2026
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Single institution experience with Tru-Cut renal mass biopsy for diagnosing Wilms tumor
Nicholas G Cost1, Candace F Granberg, Bruce J Schlomer
1Division of Pediatric Urology, Children's Medical Center of Dallas, Dallas, Texas, USA. nicholas.cost@sbcglobal.net
Purpose:
To evaluate the efficacy of needle biopsy for diagnosing Wilms tumor (WT) before chemotherapy.
Materials And Methods:
We reviewed our institutional experience with Tru-Cut biopsy of pediatric renal masses in patients who subsequently underwent nephrectomy. We compared biopsy pathology with nephrectomy specimens to determine if biopsy accurately predicted final pathology.
Results:
Seven children underwent Tru-Cut renal mass biopsy followed by surgical resection. In 4 patients, the final biopsy pathology was definitively read as WT and in 3 subjects, the pathology was read as WT versus hyperplastic nephrogenic rest. In all 7 patients, the nephrectomy pathology confirmed a diagnosis of WT. There were no complications after biopsy, and no patients have had local or regional recurrence.
Conclusion:
In our experience, pre-therapy Tru-Cut biopsy safely provides an adequate specimen for pathologic review in diagnosing WT.
