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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

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Related Experiment Video

Updated: May 13, 2026

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography
06:44

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Published on: April 13, 2018

Thrombosis in vasculitis.

Angelo L Gaffo1

  • 1Rheumatology Section, Veterans Affairs Medical Center, Birmingham, AL, USA. agaffo@uab.edu

Best Practice & Research. Clinical Rheumatology
|March 20, 2013
PubMed
Summary
This summary is machine-generated.

Thrombo-embolic disease is a known complication of vasculitis, often occurring during active disease flares. Research is exploring the underlying mechanisms and management strategies for these serious vascular events.

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Last Updated: May 13, 2026

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Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
05:37

Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis

Published on: December 22, 2017

Area of Science:

  • Rheumatology
  • Vascular Medicine
  • Immunology

Background:

  • Thrombo-embolic disease is a significant complication in various vasculitides.
  • The link between active vasculitis and thrombosis is observed but mechanistically unclear.
  • Management of thrombo-embolic events in Behçet's disease is shifting towards immunosuppression, lacking robust trial evidence.

Purpose of the Study:

  • To review the association between thrombo-embolic disease and vasculitis.
  • To highlight the role of thrombosis in specific vasculitic conditions.
  • To discuss current understanding and areas of ongoing investigation.

Main Methods:

  • Review of existing literature and ancillary data from clinical trials.
  • Analysis of observational studies.
  • Synthesis of information on vasculitis and thrombotic complications.

Main Results:

  • Confirmed association between venous thrombo-embolic disease and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
  • Recognized increased cardiovascular risk in ANCA-associated vasculitides.
  • Thrombosis is central to the pathogenesis of thromboangiitis obliterans (Buerger's disease).

Conclusions:

  • Thrombo-embolic complications are a key concern in vasculitis management.
  • Further research is needed to elucidate mechanisms and optimize treatment, particularly regarding anticoagulation versus immunosuppression.
  • The role of thrombosis in other vasculitides like giant-cell arteritis requires further investigation.