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Related Concept Videos

Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

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In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
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Introducing infectious agents and cancer.

Franco M Buonaguro1, George K Lewis, Piergiuseppe Pelicci

  • 1Viral Oncogenesis and Immunotherapy, Dpt of Experimental Oncology, Ist, Naz, Tumori "Fondazione Senatore G, Pascale, Via M, Semmola n,1, 80131 Napoli, Italy. irccsvir@unina.it.

Infectious Agents and Cancer
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PubMed
Summary

This journal explores the links between chronic infections and cancer. It covers research from basic science to clinical applications, aiding in understanding cancer development.

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Area of Science:

  • Oncology
  • Infectious Diseases
  • Translational Research

Background:

  • Chronic infections are increasingly recognized as significant contributors to cancer development.
  • Understanding the mechanisms linking infection and malignancy is crucial for prevention and treatment strategies.

Purpose of the Study:

  • To establish a dedicated open-access platform for research on infectious agents and cancer.
  • To facilitate the dissemination of basic, clinical, and translational research findings in this interdisciplinary field.

Main Methods:

  • The journal accepts original research articles, reviews, and commentaries.
  • Peer-review process ensures the quality and validity of published studies.

Main Results:

  • The journal aims to publish high-impact research on the association between chronic infections and various cancers.
  • It will cover etiological, pathogenetic, diagnostic, and therapeutic aspects.

Conclusions:

  • Infectious Agents and Cancer provides a vital resource for researchers and clinicians.
  • The journal will advance the understanding and management of infection-associated cancers.