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Published on: June 11, 2020
Perioperative myocardial infarctions are common and often unrecognized in patients undergoing hip fracture surgery
Pauliina Hietala1, Marjatta Strandberg, Niko Strandberg
1Division of Cardiology, Department of Internal Medicine, Turku University Hospital, Turku, Finland.
Insights
Hip fracture surgery patients frequently experience silent heart attacks. Early detection and treatment of perioperative myocardial infarction are crucial for improving survival rates in this population.
Area of Science:
- Cardiology
- Geriatric Medicine
- Surgical Critical Care
Background:
- Hip fractures are common in elderly patients, often necessitating surgery.
- Perioperative cardiac events, particularly myocardial infarction, pose significant risks.
- Assessing the incidence and characteristics of myocardial infarction in this cohort is critical.
Purpose of the Study:
- To determine the incidence and clinical features of acute myocardial infarction (MI) in patients undergoing surgery for hip fractures.
- To identify predictors of MI in this high-risk surgical population.
Main Methods:
- Prospective cohort study of 200 patients undergoing acute hip fracture surgery.
- Serial Troponin T (TnT) measurements and electrocardiograms (ECG) were performed.
- Diagnosis of MI based on TnT elevation and ECG changes.
Main Results:
- 35.5% of patients experienced myocardial infarction, often asymptomatic or unrecognized.
- 51% of TnT elevations occurred preoperatively.
- Independent predictors of MI included advanced age, prior revascularization, and heart failure.
Conclusions:
- Perioperative myocardial infarction is common and frequently undetected in hip fracture patients.
- Prompt diagnosis and evidence-based treatment are essential for improving outcomes.
- Further research into cardiac management protocols for this group is warranted.
Background:
The aim of this prospective cohort study was to assess the incidence and characteristics of acute myocardial infarction in patients undergoing surgery for acute hip fracture.
Methods:
A consecutive cohort of patients (n = 200, 68 men) referred to acute surgical correction of hip fracture was studied. Troponin T (TnT) measurements and electrocardiographic (ECG) recordings were performed at admission, before operation, and on the first and 2nd postoperative days, which were used for diagnosis.
Results:
The age of the patients ranged from 32 to 98 years (mean, 80.8 years), and 65 patients had a history of coronary artery disease. A significant rise in TnT as a sign of myocardial infarction was observed in 71 patients (35.5%), and 25 of them had a TnT elevation exceeding five times the upper normal limit. TnT elevation was observed in 36 patients (51%) already before surgery. Seven patients (10%) had ST elevation myocardial infarction, 23 patients (32%) had new ST depressions, and 21 patients (30%) had no new ST segment changes in the serial electrocardiographic recordings. In 40 patients (56%), the perioperative myocardial infarction was the first manifestation of coronary artery disease. Multivariate logistic regression revealed that old age (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.02-1.10; p = 0.002), earlier revascularization (OR, 3.29; 95% CI 1.12-9.73; p = 0.03), and heart failure (OR, 2.42; 95% CI 1.04-5.61; p = 0.04) were independent predictors of TnT elevation. Majority of myocardial infarctions were asymptomatic or unrecognized. Evidence-based medications of myocardial infarction were seldom started and cardiologist was consulted in 12 patients (16.9%).
Conclusion:
Patients with hip fracture often develop asymptomatic and clinically unrecognized perioperative myocardial infarctions. Earlier diagnosis and appropriate treatment of cardiac infarction may improve survival of hip fracture patients.
Level Of Evidence:
Epidemiologic study, level III.
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