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Updated: May 13, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Electrosprayed nanoparticles for drug delivery and pharmaceutical applications.
Radhakrishnan Sridhar1, Seeram Ramakrishna2
1Center for Nanofibers and Nanotechnology; National University of Singapore; Singapore, Singapore; Department of Mechanical Engineering; National University of Singapore; Singapore, Singapore.
Electrospraying is a key nanotechnology for producing pharmaceutical nanoparticles, improving drug delivery. This method enhances drug release characteristics, especially with biodegradable polymer carriers, for various therapeutic applications.
Area of Science:
- Pharmaceutical Nanotechnology
- Drug Delivery Systems
Background:
- Nanotechnology significantly impacts the pharmaceutical industry.
- Nanoparticle technology is a major component of nanotech pharma.
- Electrospraying offers solutions for nanoparticle production needs like scalability and reproducibility.
Purpose of the Study:
- To consolidate reports on electrospraying technology for nanoparticle preparation.
- To review the therapeutic application areas of electrosprayed nanoparticles.
Main Methods:
- Electrospraying of drugs with and without polymer carriers.
- Analysis of drug release characteristics.
Main Results:
- Electrospraying is effective for pharmaceutical nanoparticle preparation.
- Biodegradable polymer carriers improve sustained drug release.
- Various drugs have been successfully electrosprayed.
Conclusions:
- Electrospraying is a vital technique for pharmaceutical nanoparticle development.
- The technology shows promise for diverse therapeutic applications.
- Incorporation of polymers enhances drug encapsulation and release profiles.
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