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Histomorphologic characteristics of endomyocardial fibrosis: an endomyocardial biopsy study
P Chopra1, J Narula, K K Talwar
1Department of Pathology, All India Institute of Medical Science, Ansari Nagar, New Delhi.
Abstract:
Endomyocardial biopsies from right, left, or both ventricles were performed in 13 angiographically documented cases of endomyocardial fibrosis. The endocardium was appreciably thickened due to acellular hyalinized collagen tissue in all cases. Variable amounts of elastic tissue intimately admixed with fibrous tissue were recognized. A "zonal layering" pattern of the endocardium was absent. Thrombus, inflammatory cells, and granulation tissue at the endomyocardial interphase, and eosinophils within the biopsy were not seen. In addition, lymphomononuclear interstitial inflammatory infiltrates were seen in five cases.