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Updated: May 13, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Rational fluid management in today's ICU practice.
Karsten Bartels1, Robert H Thiele, Tong J Gan
1Department of Anesthesiology, Box 3094, Suite 5670B, Duke University Medical Center, Durham, NC 27710, USA.
Intravenous fluid therapy has advanced, focusing on patient outcomes. This review covers current intensive care unit (ICU) fluid concepts, including harmful starch-based solutions and goal-directed therapy.
Area of Science:
- Critical Care Medicine
- Pharmacology
- Clinical Practice
Background:
- Intravenous fluid therapy has evolved substantially, aiming to enhance patient outcomes.
- Early fluid administration relied on basic solutions like sodium chloride.
- Recent advancements include goal-directed fluid therapy (GDFT) utilizing dynamic indices.
Purpose of the Study:
- To provide a concise overview of contemporary intravenous fluid administration strategies in the Intensive Care Unit (ICU).
- To discuss recent clinical trial findings regarding adverse effects of specific fluid solutions.
- To highlight emerging concepts in fluid management and patient assessment.
Main Methods:
- Literature review of current concepts in intravenous fluid therapy.
- Discussion of recent clinical trial results on fluid solutions.
- Exploration of emerging technologies for fluid status assessment.
Main Results:
- Concerns exist regarding the safety of starch-based solutions in critically ill patients.
- Goal-directed fluid therapy (GDFT) is a key evolving concept.
- New methods for assessing fluid status and predicting fluid responsiveness are under development.
Conclusions:
- Continuous evolution in intravenous fluid therapy aims to optimize patient outcomes.
- Critical evaluation of new technologies is essential for improving clinical scenarios.
- Understanding current concepts and emerging trends in fluid management is crucial for ICU practice.
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