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Updated: May 13, 2026
05:02
Mechanical Micronization of Lipoaspirates for Regenerative Therapy
Published on: March 15, 2019
Juvederm ultra for lip enhancement: an open-label, multicenter study
Steven Fagien1, Corey Maas, Diane K Murphy
1sfagien@aol.com
Aesthetic Surgery Journal
|March 22, 2013
Summary
Juvéderm Ultra injectable gel effectively enhances lips, with high satisfaction rates and durable results. This study confirms its safety and efficacy for lip augmentation, utilizing new assessment scales.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Injectable Fillers
Background:
- Juvéderm Ultra injectable gel is FDA-approved for moderate to severe wrinkles and folds.
- It is also utilized for lip augmentation procedures.
Purpose of the Study:
- To evaluate the safety and effectiveness of Juvéderm Ultra for lip enhancement.
- To assess the utility of novel lip-specific effectiveness scales.
Main Methods:
- A multicenter study involving 50 subjects undergoing lip enhancement with Juvéderm Ultra.
- Evaluation of safety and effectiveness over 48 weeks using investigator, independent rater, and subject self-assessment.
- Utilized a validated Lip Fullness Scale (LFS) and an 11-point satisfaction scale.
Main Results:
- At 12 weeks, 71% of subjects achieved lip fullness goals, exceeding the 40% success criterion.
- Lip fullness improvement persisted in 56% of subjects at 24 weeks.
- Over 90% subject and investigator satisfaction was reported; side effects were mild and transient.
Conclusions:
- Juvéderm Ultra injectable gel demonstrates safety and efficacy for lip enhancement.
- Lip fullness scales offer an objective measure for treatment effectiveness assessment.
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