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Comparison of growth parameters of 5-year-old singleton children born in assisted versus natural conception
Razieh Fallah1, Mohammad Taghi Jalalian, Motahhareh Golestan
1Department of Pediatrics, Growth Disorders of Children Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Insights
Children conceived via assisted reproductive technologies (ART) showed increased rates of growth retardation by age 5. Early monitoring of physical development is crucial for ART-conceived children.
Area of Science:
- Pediatrics
- Reproductive Medicine
- Child Development
Background:
- Assisted reproductive technologies (ART) account for approximately 1% of global births.
- Concerns exist regarding the long-term health outcomes of ART-conceived children.
- This study investigates growth parameters at age 5 for children conceived via ART versus natural conception.
Purpose of the Study:
- To compare the growth parameters (weight, height, head circumference) of 5-year-old children born from assisted conception versus natural conception.
- To identify potential growth differences and developmental concerns in ART-conceived children.
Main Methods:
- A cross-sectional case-control study design was employed.
- Growth parameters of 5-year-old children were assessed.
- The study compared children born via ART (case group) with spontaneously conceived children (control group).
Main Results:
- Children born after ART exhibited a tendency towards lower birth weight and smaller head circumference.
- ART-conceived children were more likely to be underweight and have short stature at age 5.
- No significant differences were observed in sex distribution or parental age between the groups.
Conclusions:
- Growth retardation is more prevalent in children born through ART.
- Regular growth assessment and timely follow-up are essential for early detection of growth disorders in ART-conceived children.
- Educating parents on child physical development is recommended for effective monitoring.
Introduction:
At present, about 1% of newborns are delivered through assisted reproductive technologies (ART) worldwide. This study aimed to evaluate and compare the growth parameters of children born in assisted and natural conception at 5 years of age.
Materials And Methods:
In a cross-sectional case control study, weight, height and head circumference of 5-year old children were assessed. The case group consisted of term, singleton babies who were products of ART in the Center for Infertility of Shahid Sadoughi University, Yazd, Iran in 2005. The control group consisted of term, fi rst child, singleton and spontaneously conceived 5-year-old children who were referred for vaccination to primary health care center of Shahid Akbari in 2010.
Results:
Fifty-eight girls (47.5%) and 64 boys (52.5%) "with equal numbers in each of the 2 groups" were evaluated. Sex distribution, mean ages of fathers and mothers were not statistically significant different in both groups. Children born after ART tend to have lower birth weight, smaller birth head circumference and lower weight at 5 years of age. Having low birth weight (<2500 g), being underweight and having short stature at the age of 5 were more common in babies born through ART.
Conclusion:
Growth retardation is more prevalent in babies born through ART. Thus, growth assessment, parents' knowledge about child physical development, and timely and accurate follow-up of these children are necessary for early detection of any growth disorders.
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