Comparison of growth parameters of 5-year-old singleton children born in assisted versus natural conception

Razieh Fallah1, Mohammad Taghi Jalalian, Motahhareh Golestan

  • 1Department of Pediatrics, Growth Disorders of Children Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Insights

Children conceived via assisted reproductive technologies (ART) showed increased rates of growth retardation by age 5. Early monitoring of physical development is crucial for ART-conceived children.

Area of Science:

  • Pediatrics
  • Reproductive Medicine
  • Child Development

Background:

  • Assisted reproductive technologies (ART) account for approximately 1% of global births.
  • Concerns exist regarding the long-term health outcomes of ART-conceived children.
  • This study investigates growth parameters at age 5 for children conceived via ART versus natural conception.

Purpose of the Study:

  • To compare the growth parameters (weight, height, head circumference) of 5-year-old children born from assisted conception versus natural conception.
  • To identify potential growth differences and developmental concerns in ART-conceived children.

Main Methods:

  • A cross-sectional case-control study design was employed.
  • Growth parameters of 5-year-old children were assessed.
  • The study compared children born via ART (case group) with spontaneously conceived children (control group).

Main Results:

  • Children born after ART exhibited a tendency towards lower birth weight and smaller head circumference.
  • ART-conceived children were more likely to be underweight and have short stature at age 5.
  • No significant differences were observed in sex distribution or parental age between the groups.

Conclusions:

  • Growth retardation is more prevalent in children born through ART.
  • Regular growth assessment and timely follow-up are essential for early detection of growth disorders in ART-conceived children.
  • Educating parents on child physical development is recommended for effective monitoring.
Abstract

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