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Updated: May 13, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
Published on: June 30, 2016
[Optimization of conditions of Pseudomonas aeruginosa bacteriocin induction]
Abstract:
Influence of cultivation conditions on activity of bacteriocins produced by Pseudomonas aeruginosa YKM B-333 has been investigated. It was shown, that the induction of bacteriocins with maximum activity values occurs on LB medium at 28 degrees C after addition of 100 microg/ml of nalidixic acid in a late logarithmic growth phase. Using the proposed methods for induction optimization permits to improve activity of P. aeruginosa YKM B-333 bacteriocins 256 times and to reach the index of 6.5 million AU/ml.
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