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Four new sesquiterpenes from the stems of Pogostemon cablin
Fei Li1, Chuang-Jun Li, Jie Ma
1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. lifei@imm.ac.cn
Abstract:
Four new sesquiterpenes (1-4), together with four known compounds (5-8), were isolated from the stems of Pogostemon cablin (Blanco.) Benth. Their chemical structures were elucidated by means of spectroscopic methods, including 1D and 2D NMR, HRESIMS, IR, and UV. Hepatoprotective activities of these compounds were investigated, by studying the protective effect on HL-7702 cellular injury induced by dl-galactosamine.
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