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Spontaneous vesicoureteral reflux resolution in children: A ten-year single-centre experience

Peer Wildbrett1, Mandy Schwebs, J Rgen Abel

  • 1Department of Pediatric Surgery, University Children's Hospital Greifswald, Germany.

African Journal of Paediatric Surgery : AJPS
|March 23, 2013
PubMed

Insights

Vesicoureteral reflux (VUR) in infants under one year old resolves spontaneously in over 35% of cases. Children over one year with mild-moderate VUR also show a ~40% spontaneous resolution rate, supporting conservative management.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Radiology

Background:

  • Vesicoureteral reflux (VUR) is a common condition in children.
  • Understanding spontaneous resolution rates is crucial for guiding treatment strategies.

Purpose of the Study:

  • To evaluate the spontaneous resolution rate of VUR in infants and young children.
  • To inform primary treatment decisions based on age and VUR severity.

Main Methods:

  • Retrospective analysis of pediatric VUR patients treated between 2000-2010.
  • Inclusion criteria: pretreatment and follow-up voiding cystourethrogram.
  • Treatment success defined as complete VUR resolution.

Main Results:

  • Infants (<1 year) showed a 38.6% resolution rate (44 renal units).
  • Children (>1 year) demonstrated a 39.1% resolution rate (23 renal units).
  • Mild-moderate VUR (grades I-III) had higher resolution rates than severe VUR (grades IV-V) in both age groups.

Conclusions:

  • Infants with VUR, regardless of severity, have >35% spontaneous resolution, supporting conservative therapy.
  • Children over one year with mild-moderate VUR have ~40% spontaneous resolution, also favoring conservative treatment.
Abstract

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