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Related Concept Videos

Introduction to the Integumentary System01:25

Introduction to the Integumentary System

The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Accessory Structures of the Skin: Sweat Glands01:20

Accessory Structures of the Skin: Sweat Glands

Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...

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Related Experiment Video

Updated: May 13, 2026

Building Up Skin Models for Numerous Applications - from Two-Dimensional (2D) Monoculture to Three-Dimensional (3D) Multiculture
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Published on: October 20, 2023

Climate and skin function: an overview.

Babu Singh1, Howard Maibach

  • 1School of Medicine, Boston University, Boston, MA, USA. singhba@bu.edu

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|March 26, 2013
PubMed
Summary
This summary is machine-generated.

Skin health is impacted by diverse climates. Low humidity causes inflammation, while high altitudes increase UV sensitivity, and pollution accelerates skin aging. Further research is needed for optimal skincare in harsh environments.

Keywords:
altitudeclimatehumiditypollutionskintemperature

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Area of Science:

  • Dermatology and Environmental Science
  • Bioengineering and Skin Physiology

Background:

  • Global climates significantly influence skin integrity and function.
  • Limited evidence exists on skin responses to extreme climates, necessitating inference from controlled studies.
  • Noninvasive bioengineering techniques characterize skin under varied climate conditions.

Purpose of the Study:

  • To review the effects of major climate conditions on skin integrity and function.
  • To synthesize current knowledge on how environmental factors impact skin health.
  • To identify knowledge gaps regarding skin adaptation to severe climates.

Main Methods:

  • Conducted a comprehensive literature search.
  • Focused on studies investigating the impact of climate conditions on skin.
  • Utilized data from noninvasive bioengineering techniques.

Main Results:

  • Low humidity exposure in murine skin induces hyperproliferation and inflammation, manageable with topical agents or occlusion.
  • Transepidermal water loss (TEWL) and average skin temperature (Tsk) are sensitive to ambient temperature (Tambient).
  • High altitudes increase skin susceptibility to UV radiation, causing rapid surface changes. Pollution contributes to extrinsic skin aging and exacerbates dermatoses.

Conclusions:

  • Understanding skin properties in harsh climates requires further investigation.
  • Optimal skincare strategies for individuals in extreme environments need more research.
  • Bridging the gap between climate science and dermatology is crucial for public health.