Related Experiment Video
Updated: May 13, 2026

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Effect of puffing intensity on cigarette smoke yields
S W Purkis1, V Troude, C A Hill
1Imperial Tobacco Limited - P.O. Box 525, Winterstoke Rd., Bristol BS99 1LQ, UK. steve.purkis@uk.imptob.com
Predicting cigarette smoke yields like tar, nicotine, and carbon monoxide (TNCO) is possible using continuous functions based on puffing intensity. A single smoking regime can characterize cigarette products, simplifying yield analysis.
Area of Science:
- Tobacco Science
- Analytical Chemistry
- Smoke Toxicology
Background:
- Standardized smoking regimes are crucial for characterizing cigarette smoke yields.
- Understanding the relationship between smoking parameters and smoke composition is essential for product assessment.
Purpose of the Study:
- To investigate the relationship between smoking regimes and smoke yields (tar, nicotine, carbon monoxide, water).
- To establish predictive models for cigarette smoke yields based on puffing parameters.
Main Methods:
- Two US blend style cigarette products were smoked under 16 different smoking regimes.
- Yields of tar, nicotine, carbon monoxide (TNCO), and water were measured.
- Data were analyzed to identify continuous functions linked to puffing intensity and total puff volume.
Main Results:
- TNCO yields form continuous functions with puffing intensity and total puff volume, enabling yield prediction.
- TNCO yield increase rate decreases with higher puffing intensity due to faster tobacco burn.
- Water yield, relative to TNCO, increases significantly with puffing intensity.
- Total puff volume linearly relates to TNCO machine yields, human yields, and retained nicotine/solanesol.
- Smoke component concentrations are largely regime-independent, except for water, which increases exponentially with total puff volume and rapidly with intensity.
Conclusions:
- Cigarette product characterization is achievable using a single smoking regime.
- Predictive models based on puffing intensity and total puff volume can accurately estimate smoke yields.
- Smoking intensity significantly influences the relative yields of TNCO and water.
Related Concept Videos
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Chronic Obstructive Pulmonary Disease II: Emphysema
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

