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Left atrium systolic and diastolic function assessment in hypertensive patients with preserved ejection fraction

Lucia Agoston-Coldea1, S Lupu, S Hicea

  • 1"Iuliu Hatieganu" University of Medicine and Pharmacy Department of Medical Sciences Cluj-Napoca Romania "Iuliu Hatieganu" University of Medicine and Pharmacy 2-4 Clinicilor 400006 Cluj-Napoca Romania.

Acta Physiologica Hungarica
|March 26, 2013
PubMed

Insights

Left atrium remodeling is linked to diastolic dysfunction in hypertensive patients. Measuring left atrium volumes aids early detection of this condition, crucial for managing hypertension.

Area of Science:

  • Cardiology
  • Physiology
  • Hypertension Research

Background:

  • Left atrium remodeling is a common response to pressure overload in hypertension.
  • Hypertensive patients often develop left ventricle diastolic dysfunction.
  • Preserved systolic function does not exclude diastolic impairment.

Purpose of the Study:

  • To investigate the relationship between left atrium remodeling and left ventricle diastolic dysfunction.
  • To assess the utility of left atrium volume measurements in hypertensive patients.
  • To identify early markers of diastolic dysfunction in hypertension.

Main Methods:

  • Prospective study of 96 hypertensive patients and 96 controls.
  • Echocardiography used to measure left atrium volumes (reservoir, conduit, pump phases).
  • Assessment of standard left ventricle filling indices.

Main Results:

  • Hypertensive patients showed significantly higher indexed left atrium volumes.
  • Indexed left atrium volume strongly correlated with left ventricle diastolic function (p < 0.0001).
  • Diastolic dysfunction severity impacted left atrium emptying volumes.

Conclusions:

  • Left atrium indexed volume evaluation is essential for early diastolic dysfunction assessment in hypertensive patients.
  • Echocardiographic measurement of left atrium volumes provides valuable diagnostic information.
  • This method aids in the early detection and management of hypertensive heart disease.
Abstract

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