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Influence of peri-implant artifacts on bone morphometric analysis with micro-computed tomography
Jin Wook Song1, Jung Yul Cha, Till Edward Bechtold
1Department of Orthodontic, College of Dentistry of Craniofacial Deformity, Yonsei University, Seoul, Korea.
The International Journal of Oral & Maxillofacial Implants
|March 26, 2013
Summary
For accurate micro-computed tomography (micro-CT) bone analysis, a dilation pixel size of at least 5 pixels from the mini-implant is necessary. This compensates for metal artifacts, improving bone-implant contact and bone volume measurements.
Area of Science:
- Biomaterials and Dental Implants
- Medical Imaging and Diagnostics
- Orthodontics and Periodontics
Background:
- Metal artifacts from mini-implants pose challenges for accurate micro-computed tomography (micro-CT) analysis.
- Quantifying bone morphometrics around implants requires precise measurement techniques.
- Understanding the impact of imaging parameters on results is crucial for reliable data.
Purpose of the Study:
- To determine the optimal dilation pixel size distance (PSD) from mini-implants.
- To compensate for metal artifacts in micro-CT bone morphometric analysis.
- To enhance the accuracy of bone-implant contact (BIC) and bone volume/total volume (BV/TV) measurements.
Main Methods:
- 72 mini-implants were placed in beagle dogs, followed by 12 weeks of loading.
- Specimens were scanned using micro-CT at 9 μm resolution.
- Bone-implant contact (BIC) and bone volume/total volume (BV/TV) were measured at varying pixel size dilation (PSD) from the implant surface and compared to histology.
Main Results:
- Bone-implant contact (BIC) measurements decreased with increasing PSD.
- Highest correlation between micro-CT and histology for BIC was observed at 5-7 PSD (P < .05).
- Bone volume/total volume (BV/TV) showed high correlation across all PSD ranges (P < .0001).
Conclusions:
- A minimum of 5 PSD is required for accurate BIC and BV/TV measurements using micro-CT.
- This finding aids in optimizing micro-CT protocols for bone morphometric analysis around implants.
- Proper artifact compensation ensures reliable quantitative assessment of bone integration.
