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Updated: May 12, 2026
05:48
Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
Published on: September 21, 2018
Pathophysiology of exercise heart rate recovery: a comprehensive analysis
Gordon L Pierpont1, Selcuk Adabag, Demetri Yannopoulos
1Minneapolis Veterans Administration Medical Center, Minneapolis, MN 55417, USA. pierp002@umn.edu
Summary
Heart rate recovery (HRR) prolongation involves complex autonomic nervous system changes, including sinus node, sympathetic, and parasympathetic functions. This study models these autonomic shifts during exercise recovery.
Area of Science:
- Physiology
- Autonomic Nervous System Function
- Cardiovascular Regulation
Background:
- Exercise heart rate recovery (HRR) is increasingly used to assess cardiovascular health.
- Understanding the underlying pathophysiology of heart rate control during recovery is crucial.
- Existing models may not fully capture the dynamic interplay of autonomic functions during HRR.
Purpose of the Study:
- To develop a novel physiological model describing sympathetic and parasympathetic activity during the full time course of HRR.
- To test this model in a diverse group of subjects undergoing graded exercise.
- To elucidate the autonomic mechanisms contributing to prolonged HRR.
Main Methods:
- Construction of a unique physiological model based on basic principles.
- Testing the model in 22 subjects performing maximal and submaximal treadmill exercise.
- Analysis of autonomic nervous system activity during exercise and recovery phases.
Main Results:
- The model successfully describes the time course of sympathetic and parasympathetic activity during HRR.
- Prolonged HRR is associated with alterations in sinus node function.
- Changes in sympathetic function, parasympathetic function, and central autonomic regulatory mechanisms contribute to prolonged HRR.
Conclusions:
- The developed model offers a comprehensive view of autonomic control during HRR.
- Prolonged HRR reflects multifaceted alterations in autonomic regulation.
- This approach may provide novel insights into autonomic dysfunction in various health and disease states.
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