Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-patch Base Excision Repair

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:

Fractures: Bone Repair

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...

Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

Base Excision Repair

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of incremental mandibular advancement on upper airways morphology and anatomical structures: a preliminary CT scan study on body donors.

Scientific reports·2026

Same author

Antibiotics for Prophylaxis of Infective Endocarditis in Pediatric Patients: Knowledge and Prescribing Practices Between Italian Dentists.

Antibiotics (Basel, Switzerland)·2026

Same author

Pain Experience During Rapid Maxillary Expansion: A Prospective Observational Study.

Children (Basel, Switzerland)·2026

Same author

Oral Health and Quality of Life in Acromegaly: A Questionnaire-Based Study.

Dentistry journal·2025

Same author

Sleep Habits and Disorders in School-Aged Children: A Cross-Sectional Study Based on Parental Questionnaires.

Children (Basel, Switzerland)·2025

Same author

Antibiotics Use for Dental or Oral Cavity Infections in Pediatric Dentistry: Knowledge and Prescribing Practices Between Italian Dentists.

Antibiotics (Basel, Switzerland)·2025

Search research articles

Related Experiment Video

Updated: May 12, 2026

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

Published on: July 21, 2023

Bracket base remnants after orthodontic debonding.

Matteo Zanarini¹, Antonio Gracco, Monica Lattuca

¹Department of Orthodontics, University of Bologna, Bologna, Italy.

The Angle Orthodontist

|March 28, 2013

Summary

This summary is machine-generated.

Orthodontic debonding often leaves enamel remnants on bracket bases, indicating incomplete surface restoration. Some cases show clinically relevant enamel damage after bracket removal.

More Related Videos

The Establishment of a Murine Maxillary Orthodontic Model

The Establishment of a Murine Maxillary Orthodontic Model

Published on: October 27, 2023

Related Experiment Videos

Last Updated: May 12, 2026

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

Published on: July 21, 2023

The Establishment of a Murine Maxillary Orthodontic Model

The Establishment of a Murine Maxillary Orthodontic Model

Published on: October 27, 2023

Area of Science:

Dental materials science
Orthodontic technology
Biomaterials engineering

Background:

Assessing enamel surface integrity post-orthodontic debonding is crucial for patient outcomes.
Current debonding techniques aim for atraumatic removal but may leave residual material.
Understanding enamel-bracket interactions during debonding informs improved clinical practices.

Purpose of the Study:

To determine if orthodontic bracket debonding achieves complete enamel surface recovery (restitutio ad integrum).
To investigate the presence and nature of enamel within bracket base remnants after debonding using advanced imaging and spectroscopy.

Main Methods:

Microphotography and ImageJ analysis of 818 bracket bases from 60 patients.
Scanning electron microscopy (SEM) examination of 100 bracket bases for enamel presence.
Energy dispersive X-ray spectrometry (EDS) for elemental analysis (Calcium and Silicon ratios).

Main Results:

Significant differences in remnant percentage were found between incisor and canine brackets.
SEM revealed enamel on 90% of analyzed bracket bases (83% thin coat, 7% sizable fragments).
EDS confirmed Calcium presence on all brackets; Group C (no enamel evidence) showed significantly lower Ca/Si ratios.

Conclusions:

The goal of atraumatic orthodontic debonding, ensuring complete enamel recovery, is not consistently achieved.
Residual enamel on bracket bases suggests potential for enamel surface damage in some patients.
Further research into debonding protocols is needed to minimize clinical risks.