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Updated: May 12, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
[Cerebral listeria abscess in a patient with gastric cancer]
S Stöve1, A Feldmann, J Bäsecke
1Abteilung Neurologie, Katholische Kliniken Oldenburger Münsterland, St.-Josefs-Stift Cloppenburg, Cloppenburg.
Unlabelled:
HISTORY AND PRESENTATION ON ADMISSION: A 70-year-old woman with a history of gastric cancer and palliative chemotherapy was admitted with disturbed consciousness.
Investigations:
The cranial CT showed a tumor in the left parietocccipital region so that a cerebral metastasis was suspected. However further investigations including cranial MRT, liquor and blood culture collection showed that the immunocompromised patient suffered from a Listeria monocytogenes sepsis with subsequent meningitis and a cerebral abscess.
Treatment And Course:
During an antibiotic treatment with ampicillin and gentamycin a rapid neurological improvement and normalization of the liquor findings was achieved.
Conclusions:
Listeria monocytogenes is a rare but relevant cause of systemic inflammations in immunocompromised patients. The differentiation between cerebral abscess and metastasis in cancer patients can be complex but is important concerning differential therapeutic approaches.
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