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Related Concept Videos

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Urinary Bladder01:23

Urinary Bladder

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Disorders of the Urinary System

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Updated: May 12, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

A rare metastasis to the bladder.

Rishi A Modh1, Katherine A Corbyons, Lawrence L Yeung

  • 1Department of Urology, University of Florida, 1600 SW Archer Road, P.O. Box 100247, Gainesville, FL 32610, USA.

Case Reports in Urology
|March 28, 2013
PubMed
Summary
This summary is machine-generated.

Secondary bladder cancer is rare, often mimicking primary tumors. Distinguishing lung adenocarcinoma metastasis to the bladder is crucial for treatment, as demonstrated by this rare case report.

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An Orthotopic Model of Murine Bladder Cancer
09:07

An Orthotopic Model of Murine Bladder Cancer

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Last Updated: May 12, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

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Published on: December 1, 2013

An Orthotopic Model of Murine Bladder Cancer
09:07

An Orthotopic Model of Murine Bladder Cancer

Published on: February 6, 2011

Area of Science:

  • Oncology
  • Uropathology

Background:

  • Primary bladder cancer is a common malignancy, ranking fifth overall.
  • Secondary malignancies affecting the bladder are infrequent occurrences.
  • Differentiating primary bladder adenocarcinoma from metastatic disease is diagnostically challenging.

Purpose of the Study:

  • To highlight the rarity and diagnostic difficulties of secondary bladder adenocarcinoma.
  • To present a case of metastatic lung adenocarcinoma to the bladder.
  • To review existing literature on lung adenocarcinoma metastasis to the bladder.

Main Methods:

  • Case report presentation.
  • Immunohistochemical staining for diagnostic clarification.
  • Comprehensive literature review.

Main Results:

  • The presented case represents the fifth documented instance of lung adenocarcinoma metastasizing to the bladder.
  • Immunohistochemistry is vital for distinguishing the origin of bladder adenocarcinoma.
  • Metastatic adenocarcinoma to the bladder can originate from various primary sites, including prostate, colorectal, breast, and lung.

Conclusions:

  • Accurate diagnosis of secondary bladder adenocarcinoma is critical due to varying management strategies based on the primary tumor site.
  • Metastatic lung adenocarcinoma to the bladder, though rare, should be considered in the differential diagnosis.
  • Further research and case documentation are needed to better understand secondary bladder malignancies.